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DENNIS W. REMINGTON,
M.D.
A HISTORY
OF
MERIDIAN
STRESS ASSESSMENT
©1998 by Dennis W.
Remington, M.D.
All rights reserved
This document or any part thereof
may not be reproduced in any form whatsoever
without the prior written permission of
Dennis W. Remington
12411 SOUTH 265
WEST, SUITE F
DRAPER, UT 84020 USA
TOLL FREE: 1-888-224-2337
PHONE: 1-801-501-7517
FAX: 1-801-501-7518
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A HISTORY
OF MERIDIAN
STRESS
ASSESSMENT
Since late 1982,
our medical office has used sublingual provocative neutralization
techniques for treating patients with adverse reactions to inhalants,
foods, and chemicals. This technique is described in detail elsewhere, and
has been “proven” beyond any reasonable doubt by numerous double-blind
studies executed by various investigators in multiple centers and reported
in a number of peer-reviewed medical journals. For the purposes of this
paper, the original Webster's Dictionary definition of “allergy” will be
used, which is “a condition of unusual sensitivity to a substance or
substances which, in like amounts, do not affect others.” These adverse
reactions include the IgE mediated responses typically described by
traditional allergists, but also encompass other adverse reactions,
regardless of the causative mechanism.
The sublingual
testing and treatment techniques offer tremendous benefits and safety to
sensitive people compared to treatment by traditional desensitization
injections. Effective results often occur within minutes from the time
therapy is started instead of taking many months or even years as did
traditional desensitization therapy. A much more extensive range of
reactions to allergenic substances could be controlled, including
reactions to various foods and chemicals.
The testing by
provoking symptoms, and then by trial and error finding an optimal
treatment dose (neutralization dilution) which eliminated those symptoms,
was a long, laborious procedure. The provoked symptoms were often very
unpleasant for the patient.
I first heard
of meridian stress assessment (MSA) from a patient who had friends in
Phoenix, Arizona who were being treated by a medical doctor there. He used
the same sublingual application, but he used an electronic device called a
Dermatron to identify allergic substances and to help choose the
appropriate optimal treatment dilution. She made an appointment to see
him; we sent with her a list of the antigens we had tested her for and the
optimal treatment doses that she had been using. She reported back that he
had tested her for dozens of new antigens, and he identified the optimal
treatment dosages that we had chosen by provocative testing. All this was
done with no adverse reactions, and in less than an hour. Similar testing
and treatment through our system would have taken several full days.
Shortly after
this experience, I was approached by a gentleman who described himself as
a “licensed classical acupuncturist” and was told that he had an
instrument which he believed could find our optimal treatment dilutions
quickly and safely. Although very skeptical, I arranged to set up a
demonstration on a double-blind basis. We selected two patient volunteers,
both of whom had clear-cut reactions to a number of antigens, and
established treatment endpoints. We tested these two patients and
identified optimal treatment dosages for approximately 3 antigens each,
which took several hours to do. The correct dilutions were written in the
charts and not told to these patients. At the demonstration, the staff
members who had performed the testing were not present, and no one in the
room knew the correct dosages. The acupuncturist was handed between 12 and
20 bottles, containing various dilutions of the same antigen, and asked to
find the dosage of each which was the non-reactive, optimal treatment
dosage. He put each closed bottle on a plate which was hooked to the
electronic device. The patient was asked to hold on to a brass rod in one
hand, and the operator used a probe to take readings from the acupuncture
points on the fingers of her other hand. Within seconds he identified each
optimal treatment dosage correctly!
I was disturbed
by this testing because I could see no possible way in which he could have
determined those dosages, except that the instrument really did work. I
actually didn't want it to work, but the chances of his identifying the
doses by chance alone were from 1 in 3,000,000 to 1 in 64,000,000. It just
didn't fit in with anything I had ever seen or known about. He provided me
with some literature dealing with this technique, and I have since found a
great deal of other supporting literature.
I would now like
to describe a variety of other electronic instruments which utilize
electro-magnetic energy in various ways to give information regarding
bodily function. I would then like to review the literature which seems to
explain the observed phenomena, and some double-blind evidence which
provides strong support for the use of this technology.
INSTRUMENTS WHICH MEASURE PASSIVE
ELECTRICAL ENERGY:
Electrocardiograph—The
electrocardiograph was first developed in 1887 and records in a graph form
the electrical activity emanating from different areas of the heart.
Electroencephalograph—The
EEG was developed in 1875 and simply records the electrical activity
emanating from various areas of the brain.
Chinese
electric pulse testing—For
years, Chinese physicians have used various characteristics of the pulse
as diagnostic indicators of disease. In recent years they have devised a
diagnostic instrument which correlates electrical activity at the radial
pulse with he specific pulse characteristic. Pulse diagnosis can now be
done electrically.
Chinese
gastrointestinal analysis—This
instrument recently developed in China measures electrical activity of
various areas of the gastrointestinal tract in a way similar to
electrocardiography. Various patterns of activity have been correlated
with various disease states. Developers believe that this is a very safe,
non-invasive, accurate alternative to traditional western medical
examinations such as endoscopies and barium contrast study X-rays to
identify such conditions as peptic ulcers, stomach cancers, achlorhydria,
spastic colon, pancreatitis, etc.
INSTRUMENTS WHICH
MEASURE RESPONSE TO STIMULI
A) NON-ELECTROMAGNETIC
STIMULI
Stress
electrocardiogram—An
electrocardiographic tracing is taken while the patient exercises
vigorously. Subtle changes in cardiac function in response to exercise can
be identified, and early heart disease can be identified.
Sleeping or
sleep deprivation electroencephalogram—Some
abnormalities can presumably be identified on an EEG tracing if the
patient is either asleep or sleep deprived, which might otherwise be
missed if taken under normal wakeful circumstances.
Nystagmometry—Eye
movement, in response to stimulation of the ear with either cold or hot
water, is recorded electrically to identify inner ear problems.
Galvanic skin
response—The
electrical conductance between two electrodes placed on the skin is
measured. The patient is then subjected to various stimuli, and any change
in skin conductance is recorded. Any stimuli causing increased sweat
production will very quickly increase the conductance and give a change in
the readings, which are usually recorded on a graph. This technology is a
major constituent of lie detector testing. It is also used in biofeedback
technology. In a strict sense, this instrument measures the response of
the person under exposure to electric energy frequencies in the audible
range. In this case it is not as much the frequency or intensity of the
energy that influences the changes, but rather the meaning that the words
convey to the subject.
B) ELECTROMAGNETIC
STIMULI
Electromyelography—A
nerve is stimulated electrically, and the response of the muscle to that
stimulation provides useful information about the functional status of
that muscle or the integrity of its associated neurons.
Brain Stem
Audiometry—This
test involves subjecting a person to sounds of various frequencies and
intensities and then measuring the resultant brain wave activity in
response to that sound.
Cochlear
Microphonics—A
sensitive electric sensing device is placed on the cochlea of the
inner ear, and the electrical response to challenge with various sound
waves gives valuable information about cochlear function.
X-Ray—Electromagnetic
energy in the X-ray frequency is projected through a body part to be
analyzed, and the rays are collected on a photographic plate. Various body
tissues absorb the radiation at different rates, causing various shadows
to appear on the plate.
Magnetic
Resonance Imaging—The
tissues to be tested are placed in a strong magnetic field. Five different
tissue variables are utilized to construct images of various structures.
Binocular
Iriscorder—Pupillary
light reflex can be evaluated by stimulating the eye with electromagnetic
energy in the visible light frequency, and then measuring the response of
the iris. A great deal of information can be determined about the optic
nerve function and the autonomic nervous system by the characteristics of
this response. Very subtle diseases, such as pesticide toxicity,
neurological damage, and autonomic nervous system defects can be detected
with this technology.
Acupuncture
point identification—Acupuncture
points can be found by introducing a low voltage electrical charge into
the body and then measuring the electrical conductance of the skin. The
acupuncture points are more conductive (have less electrical resistance)
than the surrounding tissue.
EAV (Electroacupuncture
According to Voll) testing (or MSA, Meridian Stress Assessment)—A
low voltage electrical charge is introduced into
the
body, and the precise level of electric current conducted through
the
acupuncture points are measured. Information about various organ
systems and musculoskeletal regions is obtained by the level of the
readings. Various stimuli may be introduced, and any change in electrical
conductance at various acupuncture points provides useful diagnostic
information.
HISTORY
OF “ELECTROMEDICINE”
AND
MERIDIAN
STRESS
ASSESSMENT1
The first
reported use of electricity in medicine was in 2750 B.C., described in
Egyptian tombs, using the fish species
malopteurus
electricus.
Several descriptions of therapeutic benefits, including pain control from
exposure to the electric eel, were described by the Greeks in the first
century.
Around 1600,
William Gilbert, an English physician, coined the word “electric” and
established the difference between electricity and magnetism. In 1752,
Johann Schaeffer published the book “Electrical Medicine.” By that time,
many physicians were reportedly using electricity in their practices. In
1830, Carlo Matteucci, a professor of physics at Pisa showed that
electrical current was generated by injured tissues. In 1858, Dr. Francis,
a Philadelphia physician, was first to describe the relief of dental pain
by electricity. After 164 successful tooth extractions using “galvanism,”
he received a patent on May 26, 1858. Although his device was denounced by
the Pennsylvania Association of Dental Surgeons, the methods used by
Francis spread throughout America and Europe. In that same year, W.G.
Oliver of Buffalo claimed the discovery of “electrical anesthesia,”
reporting a 98 percent success rate using a vibrating generator for dental
pain. Again in that same year, Harding at the University College Hospital,
London, confirmed Oliver's results with studies of 40 tooth extractions.
He also set up a control subject who had results when the current was
applied but did not experience any change under the same conditions
without the current. By the late 1800s, the use of electricity in the
medicine was wide spread and described in such medical texts as Osler's
“Practice of Medicine.”
At the turn of
the century, the business atmosphere in the United States “…reflected
laissez-faire policy at its extreme. High government officials were
corrupted by the railroads, the public was swindled by flagrant
stock-market manipulations, embalmed beef was shipped to soldiers in the
Spanish-American War. Advertising contributed to the immorality of
business with its patent-medicine ads offering to cure all the real and
imagined ailments of man. There was a ‘pleasing Medicine to cure cancer,'
another to cure cholera. No promise of a quick cure was too wild, no
falsehood too monstrous.”2
A variety
of electric gadgets emerged and were marketed in a similar manner to snake
oils and other patent medicines by various charlatans. This problem,
together with the “almost total lack of standards in the medical education
and practice at that time, produced a deplorable situation.”3
To
investigate this situation, the Carnegie Foundation established a
commission headed by Abraham Flexner. The commission's final report was
published in 1910, and it produced an almost instantaneous revision of
medical education. Electrotherapy became a scientifically insupportable
technique, and it disappeared from medical practice. Doctors using
electric instruments of any sort were branded as quacks and charlatans. In
the backlash of this mind set, electronic devices of diagnostic or
therapeutic value have been slow to be accepted. Even now, a great deal of
suspicion surrounds the use of electrodiagnosis and electrotherapy.
In spite of the
virtual disappearance of all electrical therapy, investigation has
continued into the electric nature of biological systems in health and
disease states. A great deal has been discovered, and legitimate
diagnostic and therapeutic devices based on these sound discoveries have
emerged.
In the early
1950s, Reinhold Voll, a German medical doctor, developed an electronic
testing device for finding acupuncture points electrically. He was
successful in finding acupuncture points and demonstrating that these
points, known to Chinese acupuncturists for millennia, had a different
resistance to a tiny electrical current passed through the body, than did
the adjacent tissues. Many other researchers have also verified that
electrical conductance at the acupuncture points is significantly greater
than the surrounding tissue. Voll then began a lifelong search to identify
correlations between disease states and changes in the electrical
resistance of the various acupuncture points. He thought that if he could
identify electrical changes in certain acupuncture points associated with
certain diseases, then he might be able to identify those diseases more
easily, or earlier, when treatment intervention was likely to be more
effective. Voll was successful in identifying many acupuncture points
related to specific conditions and published a great deal of information
about using acupuncture points diagnostically.4
(Until
Voll, these points had been used mainly for treatment). He found, for
example, that patients with lung cancer had abnormal readings on the
acupuncture points referred to as lung points. Changes also occurred in
the electrical conductance of the acupuncture points supplying
musculoskeletal structures that are inflamed.
These changes in
acupuncture point resistance related to lung cancer have been verified
more recently by researchers from UCLA and USC. In a double-blind study, 3
patients with lung cancer and 20 controls (who had negative chest x-rays)
had the electrical resistance of several acupuncture lung points and
several small intestine points measured. There was an 87 percent
correlation between the testing results and the results of the x-ray
diagnosis for the lung points, and no correlation with the small intestine
points. Of interest, there were no false negatives and 4 “false”
positives. Two of these false positive readings were from the same patient
who had an “inconsistent shadow” on his lung X-ray but had shown no
evidence of disease with tomograms and a CT scan.5
These
“false positive” readings could have been from lung cancer not yet
diagnosed, or some other degenerative disease process, or could have been
merely incorrect readings.
Another study
from the Pain Management Clinic, Department of Anesthesiology, UCLA School
of Medicine, evaluated the ability of meridian stress assessment to
identify, in a blinded fashion, areas of pain. Forty patients were
determined by medical examination to have musculoskeletal pain. Each
patient was draped to hide any physical evidence to suggest where the pain
might be. The physician conducting the meridian stress assessment had no
prior knowledge of the patient's history, and was not allowed to talk to
the patient. Based on increased skin conductance at specific acupuncture
points of the ears, the physician determined, with greater than 75 percent
accuracy, the location of the pain, a highly significant result. This
study also pointed out that meridian stress assessment technique “is often
sensitive to pathological problems of which the patient is only minimally
aware. When some patients were told of their auricular diagnosis results,
they suddenly remembered having a minor or old pain problem in that bodily
area, a problem which they had neglected to mention during the medical
evaluation,” and thus were considered to be “misses” in the statistical
analysis.6
The
results of this test were therefore more impressive than the statistical
analysis would indicate.
A great deal has
been done throughout the world correlating changes in electrical
conductance at acupuncture points with various disease entities. Much of
the German, French, Japanese, and Chinese literature has not been
translated. Only a few examples of the many articles related to finding
and measuring acupuncture points electrically are referenced in this
paper.7–21
Voll discovered
that certain acupuncture points showed abnormal readings when subjects
were reacting allergically. He made several serendipitous discoveries
related to “allergy” testing. He noted some unusual readings on certain
acupuncture points when a patient had a bottle of medicine in his pocket.
He could remove the bottle and consistently get different readings when
the bottle was in his pocket compared to when it was not. At first he was
baffled as to how a closed bottle of medicine outside the body could
affect the acupuncture readings. It was even more baffling when he
discovered that the glass bottle of medicine could change the readings
when it was in contact anywhere along the closed electric circuit involved
with the testing procedure. Voll and his colleagues then began work to
identify the nature of this strange phenomena. They inserted a metal plate
into the circuit and demonstrated that many substances that prelude
changes in acupuncture point readings when ingested could produce the same
changes when placed on the plate (even in closed glass bottles). They
assumed that there must be some kind of electro-magnetic energy being
emitted from the substances, and that these energy fields somehow traveled
along the electric circuit to the body (perhaps like the energy waves
representing a person's voice travels along the electric circuitry of a
telephone line).
Voll and other
scientists have conducted various experiments in an attempt to
characterize the energy form that is being measured. As yet, no clear
consensus of opinion exists as to exactly how this phenomenon functions.
For that matter, no clear consensus exists how any electric phenomenon
function. Although it used to be thought that electricity was fairly
straight forward and well understood, many discoveries in the last few
years have made many scientists question older theories. Robert Beck, a
physicist well known for his pioneering work in various areas of
electromagnetism, said the following, “Man is an extremely complex
biocosmic resonator…. People ask me occasionally why this or that works
and I tell them the truth, that although I'm a physicist, I don't know
what electricity is. Neither does anybody else. But we can certainly build
a lot of marvelous things with it, from toasters to television sets to
computers. And it will be quite a few years before even the effect of some
of these simple stimulation type devices are well understood, much less
fully understood.”22
Meridian stress
assessment devices have been extensively studied by Dr. William Tiller
from Stanford, who is a professor in the Department of Materials Science
Engineering. He has written extensively in an attempt to explain the
electric behavior of the skin and how meridian stress assessment
diagnostic and treatment instruments function.23,24
Dr. Cyril
Smith, Ph.D. physicist in the Electrical Engineering Department at the
University of Salsfor, England, has also written extensively in an attempt
to explain various electromagnetic phenomena, including meridian stress
assessment on acupuncture points.25
Other
world leaders in bioelectric medicine include Robert O. Becker, M.D. and
his landmark book entitled
The Body
Electric Electromagnetism and the Foundation of Life,26”
and Bjorn
Nordenstrom, M.D. and his book
The Electric
Man27
and
Biologically Closed Electric
Circuits.28
Whether or not a
diagnostic or therapeutic modality is fully understood has absolutely no
bearing on its effectiveness or usefulness. It is beyond the scope of this
paper (and of this writer), to attempt to explain the phenomena involved
in meridian stress assessment. In fact, it would seem better to have no
explanation at all than to have an incorrect theory. For example, the drug
Hydregine has been shown to be effective for improving cerebral function
in older people in a number of double-blind controlled studies. The
mechanism was thought to be through increasing cerebral blood flow. When
further studies failed to show increased blood flow, the drug was thought
by many to be ineffective, and fell into disfavor. More recent studies
have shown a variety of actions that could explain the results of therapy,
and it once again has become widely used.29
EVIDENCE
FOR
RELIABILITY
OF MERIDIAN
STRESS
ASSESSMENT
There is a great
deal of controversy in medicine today over the issue of what techniques
are considered experimental, and which ones are considered to be
adequately proven. This issue was investigated by the Office of Technology
Assessment of the Congress of the United States.
They produced a
133 page report entitled “Assessing the Efficacy and Safety of Medical
Technologies.” This report stated that “it has been estimated that only 10
to 20 percent of all procedures currently used in medical practice have
been shown to be efficacious by controlled trails.”30
(see appendix 1)
The chairman of
the Utah Unproven Health Practices Committee in 1985 was asked what
constitutes adequate evidence that a technology has been adequately
proven? His reply was that a good double-blind study is reasonable proof,
and that several double-blind studies reported by researchers from
different centers is excellent proof. Others involved in this issue have
suggested that the agreement of experts in the field of the effectiveness
and usefulness of the technology is good proof. Also, the clinical use of
a technology by various medical practitioners is also good proof of its
efficacy.
Meridian stress
assessment instruments have been around for over thirty five years and
have been used widely in Europe and virtually around the world for allergy
testing as well as for a variety of other purposes. These instruments,
however, have been used for only a few years in this country. Meridian
stress assessment instruments have been manufactured in Germany, Japan,
China, France, Denmark, Russia, and more recently in the United States.
Many
double-blind studies have been done using this technology. In fact, most
of those practitioners who use them have set up a blinded test situation
of one kind or another before they really believe that these instruments
actually work. Besides the double-blind study described earlier in this
paper, we have tested hundreds of patients in a double-blind fashion where
the patient did not know what they were being tested for, and the
instrument operator did not know anything about the patient's reactivity.
These tests usually compare favorably to the patient's history and to
testing by other techniques.
Perhaps the most
convincing evidence for the accuracy and reliability of meridian stress
assessment came from using this testing to quickly identify correct
optimal treatment doses for patients who had unpleasant reactions to
provocative testing. An effective dose to turn off the response would
often take more than an hour by trial and error, but could almost always
be found within seconds using the instrument. On those few misses, the
optimal dose was within one dilution, and could easily be found.
Another
physician who has evaluated meridian stress assessment in his office is
William Rea, M.D. from Dallas, an internationally known pioneer in
environmental medicine. Besides serving as the director of the
Environmental Health Center in Dallas, Dr. Rea has been appointed as the
First World Professional Chair in Environmental Medicine, University of
Surrey, England. Dr. Rea set up a simple double-blind study using a number
of people who had reacted adversely to a challenge test with various
antigens, and for whom an optimal treatment dosage had been found to turn
off those reactions. Neither the patients nor the instrument operator knew
the correct dosage. A series of dilutions were tested, and the electronic
instrument identified the correct optimal treatment dosage out of 12 to 20
options in approximately 80 percent of the cases. Virtually all of the
“misses” were within 1 dilution of the optimal dose dilution determined by
trial and error, making it easy to find the optimal dose in those
“misses.” Dr. Rea describes using these instruments as part of his
practice to find optimal treatment doses for very sensitive patients
before provoking symptoms, so that he can quickly administer an effective
treatment dose in case of severe reactions.
Doctors from
England have for some time used meridian stress assessment for allergies.
One of these medical doctors reported a study in the British medical
literature.31
There have been
at least three double-blind assessments of meridian stress assessment
reported in the American medical literature. In 1989, Ali reported in the
American Journal of Clinical Pathology the results of a double-blind test
comparing the results of the IgE antibody levels (using a micro ELISA
procedure) for a variety of pollens and molds to meridian stress
assessment for the same antigens. The results showed concordance between
the two tests of 73 percent.32
In 1985, Krop did a double-blind test comparing meridian stress assessment
to sublingual and intradermal testing for a variety of foods, chemicals,
and inhalants. In 66 percent of the 227 tests, the meridian stress
assessment identified exactly the same “neutralizing” (optimal treatment)
dilution as did the intradermal and sublingual testing.33
In 1984,
researchers from the University of Hawaii compared 6 different diagnostic
modalities for assessing food allergies. These tests included history,
food challenge, skin, RAST, IgE antibodies, and meridian stress assessment
on 30 volunteers. The testing was done in a double-blind fashion, with the
patients not knowing what antigens were being tested, and the instrument
operator not knowing anything about the patient's food sensitivities. In
over 300 tests, meridian stress assessment matched the history 74
percent of the time, the food rechallenge test 77 percent of the time,
skin testing 71 percent of the time, and RAST 69 percent of the time. The
authors conclude that “the EAV(or MSA) data obtained in this experiment
demonstrates the highest degree of compatibility with the food challenge
test, which is considered to be the most sensitive of the currently
available diagnostic techniques for food allergy. In addition, the EAV (MSA)
results were comparable with both skin and RAST tests.34
(see appendix 3) In comparing these three double-blind studies, it is of
interest to note that the numbers of “false positives” identified by
meridian stress assessment greatly exceeds the number of “false
negatives.” The breakdown is as follows:

Krop points out
that in his study, the subjects were only tested to things to which they
reported an adverse response. He expressed the opinion that these apparent
“false positives” were not false at all, but merely reflected a greater
sensitivity of the meridian stress assessment compared to the more
traditional testing to which it was compared. The results of the other two
studies may also have reflected this greater sensitivity with meridian
stress assessment. When trying to evaluate the accuracy and dependability
of meridian stress assessment for food allergy testing, a number of
factors about food allergy must first be understood.
FOOD
ALLERGY
CHARACTERISTICS
1. Food allergy
is a complex issue. It is not just a yes or no situation. Various types of
food reactions have been described, including the following:
A)
Fixed allergy—A
person with a fixed food allergy will react to that substance each time
they come into contact with it, often even with a very tiny exposure. It
doesn't matter how long it has been since the last exposure, re-exposure
will still produce a reaction.
B)
Cumulative
allergy—A
person with a cumulative allergy to foods will only react to a specific
food when they ingest enough of it to exceed their allergy threshold for
that specific food. It may take a substantial amount of that food to evoke
a reaction. A specific food may be tolerated just fine one day, but if
ingested the next day will likely produce a significant reaction.
C)
Variable
allergy—A
person with variable allergies may react at certain times when eating a
food, but tolerate it well on other occasions. Some people react to
specific foods when certain pollens are in the air, but not at other
times. This may represent a complex cumulative response to common
antigenic material in several foods, or a reaction to a combination of a
food and a pollen. Some women react adversely to certain foods during a
particular phase of the menstrual cycle, or during pregnancy. In most
cases, the reason for the variability is not clear.
2. The mechanism
or mechanisms causing adverse reactions to foods are not clear. Although
much early attention was focused on the role of IgE antibodies, it is
clear that many reactions are mediated through other mechanisms. Much
recent attention has focused on the role of IgG antibodies, and some
workers believe that IgG antibodies correlate more closely with the
clinical picture of food allergy than do IgE antibodies. Prostaglandins
and related hormones have been shown to play a role in some cases. In
other cases, adverse reactions may be non-immunologic responses.
3. There is no
100 percent reliable test for food allergy to which other tests can be
compared. With no reliable standard of comparison, there is no way that
any new test can be reliably judged. Almost daily we see patients in the
office who have been tested with skin or RAST tests who are puzzled by the
results. They usually describe negative testing for foods to which they
clearly and predictably react, and positive test for foods which they have
repeatedly eliminated and reintroduced with no observable clinical
response. Each test has its limitations and shortcomings, including the
following:
A)
History—Many
patients have a history of reacting after ingesting a meal, but do not
have a clear understanding of what specific food caused the reaction. Many
patients ingest specific foods like dairy products or wheat several times
daily, and have never deliberately avoided those and other foods long
enough to see if symptoms clear. Many are puzzled by the observation that
they seem to react to a specific food sometimes, but not at other times.
Most patients do not have enough understanding of the nature of food
reactions to have intelligently evaluated individual foods.
B)
Food
Rechallenge—After
a food is avoided for a time and then reintroduced, there may be no
initial response if the reaction happens to be cumulative or variable. The
best that can be determined by a one time challenge is that the person
must not have an immediate, fixed reaction to that food. A food challenge
must be repeated several times over two days or so to rule out these other
forms of food reaction.
C)
Double-blind
food capsule test—Although
this test may work reasonably well for a fixed reaction on someone with a
low threshold for that food, it is in general a very unreliable test for
food reactivity. One study showed that this technique correlated in only
30 percent of cases with skin testing and in less than 8 percent of cases
with RAST testing.35
D)
RAST and
related tests—RAST
tests for IgE have shown a reasonable correlation to food reactions, but
it is clear that many non IgE responses occur in response to food
ingestion. IgE testing is becoming popular, and some advocates believe it
correlates better with clinical responses to food challenge. Obviously,
IgG antibodies also do not explain the whole realm of food reactivity.
E)
Skin testing—Various
types of skin responses have been investigated and are reasonably
correlated with clinical food response in some tests but not in others. It
was long thought that the skin response was mediated exclusively through
IgE antibodies. If this were the case, a better correlation between IgE
antibodies and skin responses should be shown (unless both tests simply
have a high level of error).
DISADVANTAGES
AND ADVANTAGES
OF MERIDIAN
STRESS
ASSESSMENT
Disadvantages—Antihistamines,
corticosteroids, and other medications may suppress a person's immune
reactivity, resulting in false positive readings on the instrument. Skin
testing may also be suppressed in the same way. False positive reactions
may occur in response to chemicals in the environment in which the testing
occurs (such as reactions to perfumes, cleaners, etc.) Occasionally, for
unknown reasons, the instrument fails to identify a food, chemical or
inhalant to which a person by history repeatedly reacts. The instrument
may also occasionally identify an allergen as positive, even though
avoidance and re-exposure fails to confirm that finding. Although not
perfect, double-blind studies using meridian stress assessment have shown
a better correlation with food allergy than any other known test. It is
also our clinical impression that meridian stress assessment correlates
more closely with the observations of the patient than the more
traditional forms of testing. Other advocates of meridian stress
assessment share this viewpoint. One doctor from Colorado reported the
results of a survey of 109 patients tested with this technique. All had
been tested by some other method in the past, and 69 percent thought that
the results of meridian stress assessment were more reliable than more
conventional testing, with only 5 percent reporting it is less reliable.
The rest either thought it was the same or didn't comment. Since there is
no reliable standard by which to compare meridian stress assessment, at
the present time there is no reliable way to assess its accuracy.
Perhaps the
biggest disadvantage of meridian stress assessment is the poor acceptance
of the technique by some physicians. There has been a tendency by some,
with a 1910 mentality, to dismiss it as pure “quackery” without even
knowing any more about it than it is some kind of electric device.
According to a California colleague, a state official pronounced that he
had proven that the use of meridian stress assessment instruments is pure
quackery because he had personally tested one out that he had confiscated
from a local practitioner and showed conclusively that it didn't work.
Unfortunately, all too many physicians are prepared to accept this type of
judgement, while rejecting all the world literature to the contrary. Even
back in the 1700s Johann Wolfgang von Goethe knew about this type of
mentality when he stated “we are accustomed to having man jeer at what
they do not understand.”
Advantages—Meridian
stress assessment seems to be at least as reliable, and probably more
reliable, than other forms of allergy testing available. It is much safer
than skin or challenge testing, since exposure to the allergenic substance
is minimal. It is also much more pleasant for the patient than skin
testing, since the testing itself is completely painless. There are also
no unpleasant adverse reactions, which may last for many days with skin or
challenge testing.
Meridian stress
assessment is much less expensive (in our hands) than other forms of
testing. A typical charge from a traditional allergist for a series of
skin or RAST test is often between $300 and $500. Our charge at the
present time for testing well over 100 items is $60, and that is not for
the testing per se, but rather for the doctor's, nurse's, or other
paramedical personnel's time in explaining avoidance and rechallenge
techniques, verification of results with other methods, diversified rotary
diets when indicated, and treatment options.
One of the
biggest advantages of using meridian stress assessment is in detecting
sensitivities and identifying optimal treatment dosages instead of relying
on trial and error, as used in intracutaneous serial dilution titration
techniques, or with sublingual provocative-neutralization techniques.
Another useful
application of meridian stress assessment is in testing medications. Every
doctor in primary care is faced with patients who seem to react to a lot
of different medications, and who need to be given something to control
blood pressure, or who need surgery, or who are on a lot of medications
and there is strong evidence that they are reacting to one or more of
their drugs.
There is a great
deal of concern about Iatrogenic disease these days, which is in fact
believed to be responsible for about 36 percent of hospital admissions.36
An
estimated 2 percent of hospital patients even die from iatrogenic causes.37
A great
number of these unfortunate problems are caused by adverse reactions to
drugs. Skin testing for identifying such problems are rather inadequate,
since many of the drugs are not available in an injectable form for
testing purposes. Even if an injectable form is available, the patient
still might react to the dyes, fillers, or excipients in the oral form.
Many of the reactions from drugs are non IgE, and may not even show up on
skin testing. In the past, the only option was trial and error, and it was
often after several unpleasant reactions that a tolerable, effective
choice was found. With trying to sort out a patient's problems on a lot of
drugs, it is even more complex. One has the dilemma of trying to decide
whether to stop everything and then reintroduce medications one at the
time, whether to stop only one drug at the time, or whether to try
switching some of their drugs to other types. Going off of certain
medications can be potentially dangerous to the patient. The meridian
stress assessment will usually indicate within a few minutes which
medications are likely to be a problem. This testing can also indicate
which medications are likely to be well tolerated. Based on that
information, it is generally a simple matter to avoid the problem drug,
and introduce medication likely to be well tolerated. Although this
technique is not foolproof, and may not pick up every type of adverse
reaction, it is certainly a lot better than a shot in the dark as with an
entirely trial and error approach.
We have several
patients who experienced severe reactions to the anesthetics or other
drugs used during previous surgical procedures. We have been able to test
for reactions to various classes of medications needed, find presumably
safe alternatives, and then have these drugs used by the anesthesiologist
and surgeon. In the cases in which we have participated, the patients have
tolerated the anesthesia and post surgical medications beautifully. Of
course the patients and the doctors involved were told that the testing
was no iron-clad guarantee that no reactions would occur, but would at
least provide a good chance of a reaction free procedure.
CONCLUSION
Acupuncture
points have been known for thousands of years, and the principles of
electricity have been understood (at least somewhat) since before the
1600s. It has been known for many years that acupuncture points have
different electrical conduction than the surrounding tissues. Changes in
these electrical readings in conjunction with disease states has been
investigated extensively. Using meridian stress assessment instruments for
measuring allergy responses has been around for over 35 years.
CONCLUSION
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